S1QEL

Description: S1QEL is a suppressor of mitochondrial respiratory complex I site IQ electron leak which suppresses superoxide and/or H2O2 production without altering oxidative phosphorylation. Target: Others. Smiles: CC(=O)NC1=CC(NC(=O)C(=O)NCCC2=C(C)N=C(S2)C2=CC=C(C)C=C2)=CC=C1. References: Wong HS, Benoit B, Brand MD. Mitochondrial and cytosolic sources of hydrogen peroxide in resting C2C12 myoblasts. Free Radic Biol Med. 2019 Jan,130:140-150. doi: 10.1016/j.freeradbiomed.2018.10.448. Epub 2018 Oct 31. PubMed PMID: 30389498.