(S)-(+)-Niguldipine hydrochloride

Description: (S)-(+)-Niguldipine hydrochloride is a selective alpha1A-AR antagonist used in the study of depression and epilepsy. Target: Adrenergic Receptor. Smiles: C(CCOC(=O)C=1[C@H](C(C(OC)=O)=C(C)NC1C)C2=CC(N(=O)=O)=CC=C2)N3CCC(CC3)(C4=CC=CC=C4)C5=CC=CC=C5.Cl. References: Klöckner U, et al. The dihydropyridine niguldipine modulates calcium and potassium currents in vascular smooth muscle cells. Br J Pharmacol. 1989 Jul,97(3):957-67.