Remisporine B

Description: Remisporine B is a polyketide and derivative of remisporine A that has been found inPenicilliumand has immunosuppressant activity.1,2It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 30.1 and 32.4 µg/ml, respectively).1. Target: Others. Smiles: [H][C@]12Cc3oc4cc(C)cc(O)c4c(=O)c3[C@@]3([H])c4oc5cc(C)cc(O)c5c(=O)c4[C@](O[C@]1(O)C(=O)OC)(C(=O)OC)[C@@]23[H]. References: Liu, H., Chen, S., Liu, W., et al.Polyketides with immunosuppressive activities from mangrove endophytic fungus Penicillium sp. ZJ-SY2Mar. Drugs14(12)217(2016)