Rebaudioside M

Rebaudioside M is a natural non-caloric sweetener and an agonist of the class 1 sweet taste receptor (TAS1R) heterodimer formed by TAS1R2 and TAS1R3. It is one of the minor steviol glycosides isolated from S. rebaudiana leaves. Rebaudioside M increases intracellular calcium levels in HEK293 cells expressing human TAS1R2 and TAS1R3 (EC50 = 29.54 µM) and has a relative sweetness potency 200-350 times that of sucrose. Rebaudioside M is metabolized by gut microbiota to steviol, a compound whose safety is widely studied.Formal Name: (4alpha)-13-[(O-beta-D-glucopyranosyl-(1->2)-O-[beta-D-glucopyranosyl-(1->3)]-beta-D-glucopyranosyl)oxy]-kaur-16-en-18-oic acid, O-beta-D-glucopyranosyl-(1->2)-O-[beta-D-glucopyranosyl-(1->3)]-beta-D-glucopyranosyl ester. CAS Number: 1220616-44-3. Synonyms: Reb M, Rebaudioside X. Molecular Formula: C56H90O33. Formula Weight: 1291.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Methanol: Soluble. SMILES: C[C@]1(CCC2)[C@@](CC3)([H])[C@@](CC4=C)(CC[C@]1([H])[C@]2(C)C(O[C@H](O[C@@H]5CO)[C@@H]([C@H]([C@@H]5O)O[C@]([C@@H]([C@H]6O)O)([H])O[C@@H]([C@H]6O)CO)O[C@]([C@@H]([C@H]7O)O)([H])O[C@@H]([C@H]7O)CO)=O)C[C@]43O[C@@](O[C@@H]8CO)([H])[C@@H]([C@H]([C@@H]8O)O[C@]([C@@H]([C@H]9O)O)([H])O[C@@H]([C@H]9O)CO)O[C@]([C@@H]([C@H]%10O)O)([H])O[C@@H]([C@H]%10O)CO. InChi Code: InChI=1S/C56H90O33/c1-19-11-55-9-5-26-53(2,7-4-8-54(26,3)52(77)88-50-44(86-48-40(75)36(71)30(65)22(14-59)80-48)42(32(67)24(16-61)82-50)84-46-38(73)34(69)28(63)20(12-57)78-46)27(55)6-10-56(19,18-55)89-51-45(87-49-41(76)37(72)31(66)23(15-60)81-49)43(33(68)25(17-62)83-51)85-47-39(74)35(70)29(64)21(13-58)79-47/h20-51,57-76H,1,4-18H2,2-3H3/t20-,21-,22-,23-,24-,25-,26+,27+,28-,29-,30-,31-,32-,33-,34+,35+,36+,37+,38-,39-,40-,41-,42+,43+,44-,45-,46+,47+,48+,49+,50+,51+,53-,54-,55-,56+/m1/s1. InChi Key: GSGVXNMGMKBGQU-PHESRWQRSA-N. Origin: Plant/Stevia rebaudiana.