(R,S)-AMPA (hydrate)

AMPA is the defining agonist for the AMPA subgroup of ionotropic glutamate receptors, which mediate excitatory neurotransmission. Because AMPA does not interfere with binding sites for kainic acid (Cay-78050) or NMDA (Cay-14581), it can be used to distinguish AMPA receptor-specific activity that contributes to a neuronal response. (R,S)-AMPA contains an equal mixture of the active (S)-enantiomer and the inactive (R)-enantiomer.Formal Name: alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid, hydrate. Synonyms: alpha-amino-3-hydroxy-5-methyl-4-Isoxazolepropionic Acid. Molecular Formula: C7H10N2O4 . XH2O. Formula Weight: 186.2. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 10 mM. lambdamax: 218 nm. SMILES: OC1=NOC(C)=C1CC(N)C(O)=O.O. InChi Code: InChI=1S/C7H10N2O4.H2O/c1-3-4(6(10)9-13-3)2-5(8)7(11)12,/h5H,2,8H2,1H3,(H,9,10)(H,11,12),1H2. InChi Key: HFISYNCCKQHIAM-UHFFFAOYSA-N.