(R)-(-)-Mellein

(R)-(-)-Mellein is a dihydroisocoumarin compound produced by A. ochraceus Wilhelm. It has a variety of biological activities including antibacterial, antimalarial, antifungal, and anticancer effects. (R)-(-)-Mellein inhibits proliferation of human breast cancer (MCF-7 and MDA-MB-468) and melanoma (SK-MEL-28 and Malme-3M) cell lines with IC50 values greater than 200 µM.Formal Name: 3,4-dihydro-8-hydroxy-3-methyl-1H-2-benzopyran-1-one. CAS Number: 480-33-1. Synonyms: Ochracin. Molecular Formula: C10H10O3. Formula Weight: 178.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 210, 246, 314 nm. SMILES: CC(O1)CC2=C(C(O)=CC=C2)C1=O. InChi Code: InChI=1S/C10H10O3/c1-6-5-7-3-2-4-8(11)9(7)10(12)13-6/h2-4,6,11H,5H2,1H3. InChi Key: KWILGNNWGSNMPA-UHFFFAOYSA-N.