Quercetin 3-O-beta-D-xylopyranoside

Quercetin 3-O-beta-D-xylopyranoside is a flavonoid glycoside that has been found in N. candida and has diverse biological activities. It reduces malondialdehyde (MDA) levels in isolated rat brain when used at a concentration of 10 µg/ml. Quercetin 3-O-beta-D-xylopyranoside (10, 50, and 100 µg/ml) reduces LPS- and cerulein-induced increases in reactive oxygen species (ROS) production and levels of GRP78, a marker of endoplasmic reticulum stress, in an AR42J rat pancreatic acinar cell model of pancreatitis. In vivo, quercetin 3-O-beta-D-xylopyranoside (12.5, 25, and 50 mg/kg) decreases serum TNF-alpha and IL-6 levels, myocardial MDA levels, and myocardial fibrosis, as well as improves cardiac function, in a rat model of ischemic heart failure.Formal Name: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(beta-D-xylopyranosyloxy)-4H-1-benzopyran-4-one. CAS Number: 549-32-6. Synonyms: Reinutrin, Reynoutrin. Molecular Formula: C20H18O11. Formula Weight: 434.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. lambdamax: 258, 361 nm. SMILES: O=C(C(O[C@H]1[C@@H]([C@H]([C@@H](CO1)O)O)O)=C(C2=CC(O)=C(O)C=C2)OC3=CC(O)=C4)C3=C4O. InChi Code: InChI=1S/C20H18O11/c21-8-4-11(24)14-13(5-8)30-18(7-1-2-9(22)10(23)3-7)19(16(14)27)31-20-17(28)15(26)12(25)6-29-20/h1-5,12,15,17,20-26,28H,6H2/t12-,15+,17-,20+/m1/s1. InChi Key: PZZRDJXEMZMZFD-BWYUNELBSA-N. Origin: Plant/Psidium guajava.