PTP1B-IN-4

Description: PTP1B-IN-4 (NUN-17724) is an allosteric PTP1B inhibitor with an IC50 of 8 µM. PTP1B-IN-4 can be used in studies about obesity and diabetes. Target: Phosphatase. Smiles: C(=O)(C=1C=2C(OC1CC)=CC(S(NC3=CC=C(S(NC4=NC=CS4)(=O)=O)C=C3)(=O)=O)=CC2)C5=CC(Br)=C(O)C(Br)=C5. References: Steinhauer J, et al. Drosophila lysophospholipid acyltransferases are specifically required for germ cell development. Mol Biol Cell. 2009 Dec,20(24):5224-35.