Protopanaxatriol

Description: Protopanaxatriol (20(R)-APPT), a major ginseng constituent, is a novel PPARgamma antagonist. Target: PPAR. Smiles: C[C@]12[C@@]3(C)[C@@]([C@@]([C@](CCC=C(C)C)(C)O)(CC3)[H])([C@H](O)C[C@@]1([C@]4(C)[C@@]([C@@H](O)C2)(C(C)(C)[C@@H](O)CC4)[H])[H])[H]. References: Zhang Y, et al. Protopanaxatriol, a novel PPARgamma antagonist from Panax ginseng, alleviates steatosis in mice. Sci Rep. 2014 Dec 9,4:7375.