Prasugrel

Prasugrel is a prodrug form of the platelet purinergic P2Y12 receptor antagonist R-99224. Prasugrel (0.3 and 3 mg/kg) inhibits ex vivo washed platelet aggregation in rat platelet rich-plasma. In vivo, prasugrel prevents thrombus formation (ED50 = 0.68 mg/kg) and increases tail bleeding time in rats. Formulations containing prasugrel have been used in the prevention of blood clots.Formal Name: 2-[2-(acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)-ethanone. CAS Number: 150322-43-3. Synonyms: CS 747, LY640315. Molecular Formula: C20H20FNO3S. Formula Weight: 373.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/mL, DMSO: Slightly soluble, PBS (pH 7.2): 0.25 mg/mL. SMILES: CC(OC1=CC2=C(S1)CCN(C(C(C3CC3)=O)C4=CC=CC=C4F)C2)=O. InChi Code: InChI=1S/C20H20FNO3S/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21/h2-5,10,13,19H,6-9,11H2,1H3. InChi Key: DTGLZDAWLRGWQN-UHFFFAOYSA-N.