Pramoxine (hydrochloride)

Pramoxine is a local anesthetic. It reduces electrically induced peak compound action potential (CAP) amplitudes in isolated frog sciatic nerve (IC50 = 0.21 mM). Topical administration of pramoxine (0.35 and 0.6%) inhibits winking in a rabbit corneal test, indicating anesthetic activity. It inhibits the pinprick-induced cutaneous trunci muscle reflex (CTMR) in the skin of rats (ED50 = 42.1 µmol, s.c.).Formal Name: 4-[3-(4-butoxyphenoxy)propyl]-morpholine, monohydrochloride. CAS Number: 637-58-1. Synonyms: Pramocaine. Molecular Formula: C17H27NO3 . HCl. Formula Weight: 329.9. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 5mg/mL, DMSO: 5mg/mL, Ethanol: 15mg/mL, Ethanol:PBS (pH 7.2) (1:5): 0.16mg/mL. lambdamax: 227 nm. SMILES: CCCCOC1=CC=C(OCCCN2CCOCC2)C=C1.Cl. InChi Code: InChI=1S/C17H27NO3.ClH/c1-2-3-12-20-16-5-7-17(8-6-16)21-13-4-9-18-10-14-19-15-11-18,/h5-8H,2-4,9-15H2,1H3,1H. InChi Key: SYCBXBCPLUFJID-UHFFFAOYSA-N.