PPADS (sodium salt)

PPADS (sodium salt)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay14537-10 10 mg -

6 - 10 Werktage*

61,00 €
Cay14537-50 50 mg -

6 - 10 Werktage*

250,00 €
Cay14537-250 250 mg -

6 - 10 Werktage*

1.090,00 €
 
P2X and P2Y purinergic receptors are ATP-sensitive receptors responsible for mediating a large... mehr
Produktinformationen "PPADS (sodium salt)"
P2X and P2Y purinergic receptors are ATP-sensitive receptors responsible for mediating a large variety of excitatory postsynaptic responses including fast transmission at central synapses, contraction of smooth muscle cells, platelet aggregation, macrophage activation, and apoptosis. PPADS is a non-selective P2 purinergic antagonist that blocks recombinant P2X1-5 (IC50s = 1-2.6 µM), native P2Y2-like (IC50 = ~0.9 mM), and recombinant P2Y4 (IC50 = ~15 mM) receptors. PPADS antagonism of ATP-sensitive P2 receptors produces neuroprotective effects in an ischemia model with permanent middle cerebral artery occlusion in spontaneously hypertensive rats.Formal Name: 4-[2-[4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-2-pyridinyl]diazenyl]-1,3-benzenedisulfonic acid, tetrasodium salt. CAS Number: 192575-19-2. Synonyms: Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid. Molecular Formula: C14H10N3O12PS2 . 4Na. Formula Weight: 599.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: Slightly soluble. lambdamax: 363, 482 nm. SMILES: [H]C(C1=C(COP([O-])([O-])=O)C(/N=N/C2=C(S([O-])(=O)=O)C=C(S([O-])(=O)=O)C=C2)=NC(C)=C1O)=O.[Na+].[Na+].[Na+].[Na+]. InChi Code: InChI=1S/C14H14N3O12PS2.4Na/c1-7-13(19)9(5-18)10(6-29-30(20,21)22)14(15-7)17-16-11-3-2-8(31(23,24)25)4-12(11)32(26,27)28,,,,/h2-5,19H,6H2,1H3,(H2,20,21,22)(H,23,24,25)(H,26,27,28),,,,/q,4*+1/p-4/b17-16+,,,,. InChi Key: KURWUCJJNVPCHT-PGXCWKBOSA-J.
Schlagworte: Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid, 4-[2-[4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-2-pyridinyl]diazenyl]-1,3-benzenedisulfonic acid, tetrasodium salt
Hersteller: Cayman Chemical
Hersteller-Nr: 14537

Eigenschaften

Anwendung: P2 purinergic receptor antagonist
MW: 599.3 D
Formel: C14H10N3O12PS2 . 4Na
Reinheit: >95%
Format: Solid

Datenbank Information

CAS : 192575-19-2| Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H315, H319, H335
P-Sätze: P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "PPADS (sodium salt)"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen