Povidone-Iodine

Povidone-iodine is a microcide with broad-spectrum activity against bacteria, fungi, viruses, and protozoans. It reduces total anaerobic and aerobic bacterial counts in vitro in dog feces when applied topically as a 10% solution. Povidone-iodine decreases bacterial counts and the occurrence of anastomotic leaks in a dog model of emergent resection and anastomosis of the sigmoid colon when applied in situ at a concentration of 10% v/v. Topical administration of povidone-iodine (10% v/v) also reduces bacterial counts on the skin of cynomolgus monkeys. Formulations containing povidone-iodine have been used to disinfect skin before and after surgery.Formal Name: 1-ethenyl-2-pyrrolidinone, homopolymer, compd. with iodine. CAS Number: 25655-41-8. Synonyms: Iodopovidone, NSC 26245, Polyvinylpyrrolidone-Iodine. Molecular Formula: (C6H9NO)n .XI2. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble, Water: soluble. SMILES: O=C1CCCN1C(C)CC.II.