Podocarpusflavone A

Description: Podocarpusflavone A is a DNA topoisomerase I inhibitor with moderate anti-proliferative activity that induces cell apoptosis in MCF-7. Target: STAT, Topoisomerase. Smiles: COc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(=O)c4c(O)cc(O)cc4o3)c2o1. References: Pen-Ho Yeh et al. Naturally Occurring Cytotoxic [3'->8'']-Biflavonoids from Podocarpus nakaii J Tradit Complement Med. 2012 Jul,2(3):220-6.