Piracetam-d6

Piracetam-d6 is intended for use as an internal standard for the quantification of piracetam by GC- or LC-MS. Piracetam is a nootropic cyclic GABA derivative. It is a positive allosteric modulator of AMPA receptors and enhances binding of the NMDA antagonist MK-801 to rat forebrain membranes. Piracetam (1 mM) protects against amyloid-beta-induced decreases in the mitochondrial membrane potential, as well as decreases in neurite outgrowth in the presence of NGF, in PC12 rat adrenal medulla cells. It prevents scopolamine-induced amnesia in a passive avoidance test in mice when administered at a dose of 30 mg/kg. Formulations containing piracetam have been used in the treatment of myoclonus.Formal Name: 2-oxo-1-pyrrolidine-3,3,4,4,5,5-d6-acetamide. CAS Number: 2907016-93-5. Molecular Formula: C6H4D6N2O2. Formula Weight: 148.2. Purity: >99% deuterated forms (d1-d6). Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble, Methanol: soluble, Water: soluble. SMILES: NC(CN1C(C([2H])([2H])C([2H])([2H])C1([2H])[2H])=O)=O. InChi Code: InChI=1S/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9)/i1D2,2D2,3D2. InChi Key: GMZVRMREEHBGGF-NMFSSPJFSA-N.