Piperlonguminine

Description: Piperlonguminine, an alkaloid amide isolated from the Piper species, exhibits anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal, and antibacterial activities. It inhibits Akt/mTOR signaling, promotes autophagy, and mediates cancer cell death. Target: Antibiotic, Anti-infection, Antifungal, Antibacterial. Smiles: CC(C)CNC(=O)\C=C\C=C\c1ccc2OCOc2c1. References: Inhibitory effect of piperlonguminine on melanin production in melanoma B16 cell line by downregulation of tyrosinase expression.Pigment Cell Res. 2006 Feb,19(1):90-8.