Picrotin

Description: Picrotin is an inhibitor of glycine receptors. Picrotin blocks alpha2 GlyR, alpha1 GlyR, and alpha3 GlyR and can be used in studies about neurotransmission. Target: Chloride channel. Smiles: [H][C@@]12OC(=O)[C@@]([H])([C@]1([H])C(C)(C)O)[C@]1(O)C[C@H]3O[C@]33C(=O)O[C@@]2([H])[C@]13C. References: Li P, et al. Gating effects on picrotin block of glycine receptors. Neuroreport. 2012 Dec 5,23(17):1017-20.