Piceatannol

Description: Piceatannol (Astringenin) is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-kappaB activation and gene expression of TNF-induced. It is synthetic from the conversion of resveratrol by cytochrome P450 1B1. Target: PKA, Syk, Apoptosis, Serine/threonin kinase, Autophagy, PKC. Smiles: C(=C/C1=CC(O)=CC(O)=C1)\C2=CC(O)=C(O)C=C2. References: Oliver JM, et al. J Biol Chem, 1994, 269(47), 29697-29703.