Piceatannol

Piceatannol is a stilbene that has been found in red wine and an active metabolite of trans-resveratrol (Cay-70675), a polyphenol with diverse biological activities. It is formed from trans-resveratrol by the cytochrome P450 (CYP) isoform CYP1B1. Piceatannol induces apoptosis in BJAB B cell lymphoma cells (EC50 = 25 µM). Dietary administration of piceatannol (0.025% w/w) improves intestinal epithelial barrier integrity, prevents decreases in colon length, and increases body weight in a mouse model of ulcerative colitis induced by dextran sodium sulfate (DSS, Cay-23250).Formal Name: 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-1,2-benzenediol. CAS Number: 10083-24-6. Synonyms: Astringenin, trans-Picetannol, trans-3,3',4,5'-Tetrahydroxystilbene. Molecular Formula: C14H12O4. Formula Weight: 244.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 3 mg/ml, DMSO: 5 mg/ml, Ethanol: 10 mg/ml, Ethanol:PBS (pH 7.2) (1:2): 0.3 mg/ml. lambdamax: 221, 327 nm. SMILES: Oc1cc(\C=C/c2ccc(O)c(O)c2)cc(O)c1. InChi Code: InChI=1S/C14H12O4/c15-11-5-10(6-12(16)8-11)2-1-9-3-4-13(17)14(18)7-9/h1-8,15-18H/b2-1+. InChi Key: CDRPUGZCRXZLFL-OWOJBTEDSA-N.