PF-02545920

Description: PF-02545920, a PDE10 inhibitor, is used potentially for the treatment of Huntington's Disease. Target: Others. Smiles: CN1C=C(C(=N1)C=2C=CN=CC2)C3=CC=C(OCC4=NC5=C(C=C4)C=CC=C5)C=C3. References: Delnomdedieu M, Forsberg A, Ogden A, Fazio P, Yu CR, Stenkrona P, Duvvuri S, David W, Al-Tawil N, Vitolo OV, Amini N, Nag S, Halldin C, Varrone A. In vivo measurement of PDE10A enzyme occupancy by positron emission tomography (PET) following single oral dose administration of PF-02545920 in healthy male subjects. Neuropharmacology. 2017 Jan 22,117:171-181. doi: 10.1016/j.neuropharm.2017.01.016. [Epub ahead of print] PubMed PMID: 28122201.