Patulin

Patulin is a mycotoxin originally isolated from P. griseofulvum. It is lethal to rodents (LD50 = 29-55 mg/kg) and poultry (LD50 = 170 mg/kg), as well as induces convulsions, dyspnea, pulmonary edema and ulceration, and gastrointestinal distension in rats, mice, chickens, and hamsters. Patulin is embryotoxic in chick eggs when used at concentrations ranging from 2.35 to 68.7 µg/egg and induces hypoplasia of the mesencephalon and telencephalon, hyperplasia of the mandibular process, and growth retardation in rat embryos. It has been found in Penicillium-infected apple crops.Formal Name: 4-hydroxy-4H-furo[3,2-c]pyran-2(6H)-one. CAS Number: 149-29-1. Synonyms: Clairformin, Expansin, Mycoin C, NSC 8120, NSC 32951, Penicidin, Terinin. Molecular Formula: C7H6O4. Formula Weight: 154.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 10 mg/ml, Ethanol: 13 mg/ml, PBS (pH 7.2): 5 mg/ml. lambdamax: 275 nm. SMILES: O=C1OC2=CCOC(O)C2=C1. InChi Code: InChI=1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2. InChi Key: ZRWPUFFVAOMMNM-UHFFFAOYSA-N.