Pantothenate-AMC

Pantothenate-AMC is a fluorogenic substrate for vanin-1, an enzyme involved in the recycling of L-pantothenic acid. Upon enzymatic cleavage by vanin-1, 7-amino-7-methylcoumarin (AMC) is released and its fluorescence can be used to quantify vanin-1 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.Formal Name: (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-[(4-methyl-2-oxo-2H-1-benzopyran-7-yl)amino]-3-oxopropyl]-butanamide. CAS Number: 1224691-12-6. Synonyms: Pantothenate-7-amino-4-methylcoumarin. Molecular Formula: C19H24N2O6. Formula Weight: 376.4. Purity: >95%. Emission: 440-460 nm. Excitation: 340-360 nm. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: Slightly Soluble: 0.1-1 mg/ml, DMSO: Sparingly Soluble: 1-10 mg/ml, Water: Slightly Soluble: 0.1-1 mg/ml. SMILES: CC(C1=CC=C(NC(CCNC([C@H](O)C(C)(C)CO)=O)=O)C=C1O2)=CC2=O. InChi Code: InChI=1S/C19H24N2O6/c1-11-8-16(24)27-14-9-12(4-5-13(11)14)21-15(23)6-7-20-18(26)17(25)19(2,3)10-22/h4-5,8-9,17,22,25H,6-7,10H2,1-3H3,(H,20,26)(H,21,23)/t17-/m0/s1. InChi Key: QMSSTHIQHBHLMP-KRWDZBQOSA-N.