p-Cresol Glucuronide

p-Cresol glucuronide is a metabolite of p-cresol, a uremic toxin formed by bacterial fermentation of proteins in the large intestine. It is formed from p-cresol primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT1A6, but also by UGT1A9, in human liver and kidney microsomes. p-Cresol glucuronide accumulates in feces, blood, and urine of patients with chronic kidney disease (CKD).Formal Name: 4-methylphenyl beta-D-glucopyranosiduronic acid. Synonyms: 4-Cresol Glucuronide, p-Tolyl-beta-D-glucuronide. Molecular Formula: C13H16O7. Formula Weight: 284.3. Purity: >90%. Formulation: (Request formulation change), A solid. Solubility: Ethanol: soluble. lambdamax: 220 nm. SMILES: OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC2=CC=C(C=C2)C)=O. InChi Code: InChI=1S/C13H16O7/c1-6-2-4-7(5-3-6)19-13-10(16)8(14)9(15)11(20-13)12(17)18/h2-5,8-11,13-16H,1H3,(H,17,18)/t8-,9-,10+,11-,13+/m0/s1. InChi Key: JPAUCQAJHLSMQW-XPORZQOISA-N.