Oxipurinol

Oxipurinol is an inhibitor of xanthine oxidase and active metabolite of the xanthine oxidase inhibitor allopurinol (Cay-10012597). Oxipurinol is formed by the oxidation of allopurinol and binds to an enzyme-bound molybdenum cofactor that keeps xanthine oxidase in an inactive state. It inhibits de novo purine and pyrimidine biosynthesis in human fibroblast cultures. Oxipurinol also inhibits the growth of L. donovani when used at concentrations ranging from 20 to 50 µg/ml.Formal Name: 1H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione. CAS Number: 2465-59-0. Synonyms: Alloxanthine, NSC 76239. Molecular Formula: C5H4N4O2. Formula Weight: 152.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 3 mg/ml, DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml. lambdamax: 254 nm. SMILES: O=C1C2=C(NN=C2)NC(N1)=O. InChi Code: InChI=1S/C5H4N4O2/c10-4-2-1-6-9-3(2)7-5(11)8-4/h1H,(H3,6,7,8,9,10,11). InChi Key: HXNFUBHNUDHIGC-UHFFFAOYSA-N.