OXF BD 02

Description: OXF BD 02 is a potent and selective BRD4(1) inhibitor (IC50: 382 nM) with anticancer and anti-inflammatory activity. Target: Epigenetic Reader Domain. Smiles: CC=1C(C2=CC(C(O)C3=CC=CC=C3)=CC(O)=C2)=C(C)ON1. References: Hewings DS, et al. Optimization of 3,5-dimethylisoxazole derivatives as potent bromodomain ligands. J Med Chem. 2013 Apr 25,56(8):3217-27.