OPHIOPOGONIN D

Description: Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-kappaB nuclear translocation. Target: PPAR, NF-kappaB, RAAS, Calcium Channel. Smiles: C[C@@]12[C@@]3([C@](C[C@]1([C@]4([C@](CC2)([C@@]5(C)[C@H](O[C@H]6[C@H](O[C@H]7[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O7)[C@@H](O[C@H]8[C@H](O)[C@@H](O)[C@H](O)CO8)[C@@H](O)[C@@H](C)O6)C[C@H](O)CC5=CC4)[H])[H])[H])(O[C@@]9([C@H]3C)CC[C@@H](C)CO9)[H])[H]. References: Huang X , Wang Y , Zhang Z , et al. Ophiopogonin D and EETs ameliorate Ang II-induced inflammatory responses via activating PPARalpha in HUVECs[J]. Biochemical and Biophysical Research Communications, 2017:S0006291X17311166.