OGT 2115

OGT 2115 is an inhibitor of heparanase (IC50 = 0.4 µM), an enzyme that cleaves heparan sulfate into glucuronic acid (GlcUA) and N-acetylglucosamine (GlcNAc). OGT 2115 (10 µM) inhibits herpes simplex virus 2 (HSV-2) infection of VK2/E6E7 vaginal epithelial cells.Formal Name: 2-[4-[[3-(4-bromophenyl)-1-oxo-2-propen-1-yl]amino]-3-fluorophenyl]-5-benzoxazoleacetic acid. CAS Number: 853929-59-6. Molecular Formula: C24H16BrFN2O4. Formula Weight: 495.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. SMILES: BrC1=CC=C(/C=C/C(NC2=C(F)C=C(C3=NC4=C(C=CC(CC(O)=O)=C4)O3)C=C2)=O)C=C1. InChi Code: InChI=1S/C24H16BrFN2O4/c25-17-6-1-14(2-7-17)4-10-22(29)27-19-8-5-16(13-18(19)26)24-28-20-11-15(12-23(30)31)3-9-21(20)32-24/h1-11,13H,12H2,(H,27,29)(H,30,31)/b10-4+. InChi Key: LKBXWNYXDMSFQU-ONNFQVAWSA-N.