OAC3

Octamer-binding transcription factor 4 (Oct4) is a transcription factor which, with Sox2, Klf4, and c-Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells. OAC3 is an Oct4-activating compound which activates expression through the Oct4 gene promoter. In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC3 (1 µM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells from embryonic fibroblasts.Formal Name: 4-fluoro-N-1H-indol-5-yl-benzamide. CAS Number: 182564-41-6. Molecular Formula: C15H11FN2O. Formula Weight: 254.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMF:PBS(pH 7.2)(1:1): 0.50 mg/ml, DMSO: 16 mg/ml, Ethanol: 12.5 mg/ml. lambdamax: 224, 264 nm. SMILES: O=C(NC1=CC=C(NC=C2)C2=C1)C3=CC=C(F)C=C3. InChi Code: InChI=1S/C15H11FN2O/c16-12-3-1-10(2-4-12)15(19)18-13-5-6-14-11(9-13)7-8-17-14/h1-9,17H,(H,18,19). InChi Key: RQJUZWRDCVBOMH-UHFFFAOYSA-N.