Nirmatrelvir

Description: PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) . Target: SARS-CoV. Smiles: C(N[C@@H](C[C@H]1C(=O)NCC1)C#N)(=O)[C@@H]2[C@@]3([C@@](C3(C)C)(CN2C([C@@H](NC(C(F)(F)F)=O)[C@](C)(C)C)=O)[H])[H]. References: Li J, et al. Nirmatrelvir exerts distinct antiviral potency against different human coronaviruses. Antiviral Res. 2023 Mar,211:105555.