NG,NG-dimethyl-L-Arginine dihydrochloride

Description: NG,NG-dimethyl-L-Arginine dihydrochloride is an endogenous nitric oxide synthase inhibitor. Nitric oxide (NO) that is synthesised from L-arginine contributes to the regulation of blood pressure and to host defence[1]. Target: NO Synthase. Smiles: N[C@@H](CCCNC(N(C)C)=N)C(O)=O.[H]Cl.[H]Cl. References: Wu M, et al. Renal asymmetric dimethylarginine inhibits fibrosis. FEBS Open Bio. 2020 Oct,10(10):2003-2009. doi: 10.1002/2211-5463.12949. Epub 2020 Aug 30.