N-Propionylglycine

N-Propionylglycine is a glycine-conjugated form of propionic acid. It is produced by glycine-N-acylase from propionyl-CoA, a catabolic intermediate that accumulates when the activity of propionyl-CoA carboxylase, the enzyme that converts propionyl-CoA to methylmalonyl-CoA, is deficient, in the mitochondria. Urinary levels of N-propionylglycine are increased in patients with propionic acidemia, an inborn error of metabolism characterized by vomiting, lethargy, protein intolerance, and failure to thrive.Formal Name: N-(1-oxopropyl)-glycine. CAS Number: 21709-90-0. Synonyms: NSC 158539. Molecular Formula: C5H9NO3. Formula Weight: 131.1. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 15 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: O=C(CNC(CC)=O)O. InChi Code: InChI=1S/C5H9NO3/c1-2-4(7)6-3-5(8)9/h2-3H2,1H3,(H,6,7)(H,8,9). InChi Key: WOMAZEJKVZLLFE-UHFFFAOYSA-N.