N-Oleoyl Valine

N-Oleoyl valine is an endogenous N-acyl amine that acts as an antagonist at the transient receptor potential vanilloid type 3 (TRPV3) receptor, which is involved in thermoregulation. N-Oleoyl valine is increased in mice following cold exposure for up to at least 16 days. Acute lung injury in mice increases the concentration of N-Oleoyl valine in lung tissue. N-acyl amines also promote mitochondrial uncoupling.Formal Name: N-[(9Z)-1-oxo-9-octadecen-1-yl]-L-valine. CAS Number: 60374-41-6. Molecular Formula: C23H43NO3. Formula Weight: 381.6. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 10 mg/ml, DMSO: 12 mg/ml, Ethanol: 12 mg/ml, Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml. lambdamax: 203 nm. SMILES: CCCCCCCC/C=C\CCCCCCCC(N[C@@H](C(C)C)C(O)=O)=O. InChi Code: InChI=1S/C23H43NO3/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21(25)24-22(20(2)3)23(26)27/h11-12,20,22H,4-10,13-19H2,1-3H3,(H,24,25)(H,26,27)/b12-11-/t22-/m0/s1. InChi Key: LRQPUGFHAACUMH-GJCOWUBNSA-N.