N-Butanoyl-L-homoserine lactone

Description: N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It exhibits antibacterial activity and is employed in antibacterial biofilm[1]. Target: ADC Linker, Antibacterial. Smiles: CCCC(=O)N[C@H]1CCOC1=O. References: Keith Alan Charlton, et al. Methods for the Treatment of an Infectious Bacterial Disease with an Anti-Lactone or Lactone Derived Signal Molecules Antibody. US20130045208A1