Myricetin

Myricetin is a flavonoid compound found in many fruits and vegetables, including red wine, that acts as a powerful antioxidant. Myricetin inhibits TBARS formation with an IC50 value of 6.34 and at 20 µM, blocks oxLDL uptake by U937-derived macrophages, reducing CD36 expression. Myricetin demonstrates potent chemopreventative potential by binding JAK1/STAT3 to inhibit the neoplastic transformation of murine JB6 P+ cells and inhibiting MEK1 kinase activity.Formal Name: 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one. CAS Number: 529-44-2. Synonyms: Cannabiscetin, LDN-0014058, NSC 407290. Molecular Formula: C15H10O8. Formula Weight: 318.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, DMSO:PBS (pH 7.2) (1:10): 0.5 mg/ml, Ethanol: 1 mg/ml. lambdamax: 255, 376 nm. SMILES: Oc1cc(O)c2c(c1)oc(c1cc(O)c(O)c(O)c1)c(O)c2=O. InChi Code: InChI=1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H. InChi Key: IKMDFBPHZNJCSN-UHFFFAOYSA-N. Origin: Synthetic.