MNI-caged-L-glutamate (trifluoroacetate salt)

MNI-caged-L-glutamate is a form of glutamate linked to a 4-methoxy-7-nitroindolinyl (MNI) photoprotecting group that is pharmacologically inactive at neuronal glutamate receptors (up to mM concentrations). Upon exposure to light (300 - 380 nm excitation), L-glutamate is cleaved of MNI and released within submicroseconds. This compound can be used to investigate the mechanisms of fast synaptic glutamate receptors in situ.Formal Name: (alphaS)-alpha-amino-2,3-dihydro-4-methoxy-7-nitro-delta-oxo-1H-indole-1-pentanoic acid, 2,2,2-trifluoroacetate. CAS Number: 2226362-29-2. Molecular Formula: C14H17N3O6 . CF3COOH. Formula Weight: 437.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: :, Ethanol: 0.25 mg/ml, PBS (pH 7.2): 5 mg/ml. lambdamax: 213, 249, 304 nm. SMILES: COC1=C2C(N(C(CC[C@H](N)C(O)=O)=O)CC2)=C([N+]([O-])=O)C=C1.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C14H17N3O6.C2HF3O2/c1-23-11-4-3-10(17(21)22)13-8(11)6-7-16(13)12(18)5-2-9(15)14(19)20,3-2(4,5)1(6)7/h3-4,9H,2,5-7,15H2,1H3,(H,19,20),(H,6,7)/t9-,/m0./s1. InChi Key: YHZQLUFSVKYSRH-FVGYRXGTSA-N.