MMG-0358

MMG-0358 is an inhibitor of indolamine 2,3-dioxygenase 1 (IDO1, IC50s = 2 and 80 nM for the mouse and human enzyme, respectively). It is selective for IDO1 over tryptophan 2,3-dioxygenase (TDO, IC50s = >100 µM for mouse and human TDO).Formal Name: 4-chloro-2-(1H-1,2,3-triazol-5-yl)-phenol. CAS Number: 1378976-02-3. Molecular Formula: C8H6ClN3O. Formula Weight: 195.6. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 20 mg/ml, DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml, DMSO: 15 mg/ml, Ethanol: 15 mg/ml. lambdamax: 214, 247, 304 nm. SMILES: ClC1=CC=C(O)C(C2=CN=NN2)=C1. InChi Code: InChI=1S/C8H6ClN3O/c9-5-1-2-8(13)6(3-5)7-4-10-12-11-7/h1-4,13H,(H,10,11,12). InChi Key: NBDFMTBYKCBTSW-UHFFFAOYSA-N.