Mevastatin

Description: Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials. Target: Autophagy, Antibiotic, Lipid, Antibacterial, Apoptosis, HMG-CoA Reductase. Smiles: C(C[C@@H]1C[C@@H](O)CC(=O)O1)[C@@H]2[C@]3([C@@H](OC([C@H](CC)C)=O)CCC=C3C=C[C@@H]2C)[H]. References: Endo A, et al. J Antibiot (Tokyo), 1976, 29(12), 1346-1348.