Metergoline

Description: Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPT INE as a dopamine agonist and also for migraine disorder therapy. Target: Sodium Channel, 5-HT Receptor, Dopamine Receptor. Smiles: CN1C2=C3C([C@@]4([C@@](CC3=C1)(N(C)C[C@H](CNC(OCC5=CC=CC=C5)=O)C4)[H])[H])=CC=C2. References: Knight, A.R.,Misra, A.,Quirk, K., et al. Pharmacological characterisation of the agonist radioligand binding site of 5-HT2A, 5-HT2B and 5-HT2C receptors. Naunyn Schmiedebergs Arch. Pharmacol. 370(2), 114-123 (2004)