Luteolin

Description: Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor. Luteolin has a wide range of biological activities including antitumor, antioxidant, anti-inflammatory, antimicrobial, antiviral, antiallergic, and procoagulant. Target: PDE, Apoptosis, Autophagy, Endogenous Metabolite, Nrf2. Smiles: O=C1C=2C(OC(=C1)C3=CC(O)=C(O)C=C3)=CC(O)=CC2O. References: Chen P, et al. Luteolin inhibits cell proliferation and induces cell apoptosis via down-regulation of mitochondrial membrane potential in esophageal carcinoma cells EC1 and KYSE450. Oncotarget. 2017 Apr 18,8(16):27471-27480.