Limonin

Limonin is the first described limonoid, which are naturally occurring tetranortriterpenoids that impart bitter flavor in citrus fruits. Compounds belonging to this group have reported anti-proliferative and proapoptotic activity on several cancer cell lines as well as pesticidal, anti-malarial, anti-microbial, and anti-HIV activity.Formal Name: (2aR,4aR,4bR,5aS,8S,8aS,10aR,10bR,14aS)-8-(3-furanyl)decahydro-2,2,4a,8a-tetramethyl-11H,13H-oxireno[d]pyrano[4',3':3,3a]isobenzofuro[5,4-f][2]benzopyran-4,6,13(2H,5aH)-trione. CAS Number: 1180-71-8. Synonyms: di-delta-lactone Limonoic Acid. Molecular Formula: C26H30O8. Formula Weight: 470.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml, DMSO: 10 mg/ml. SMILES: CC1(C)[C@]2([H])CC([C@@]3(C)[C@@]4(O5)[C@H]5C(O[C@@H](C6=COC=C6)[C@]4(C)CC[C@]3([H])[C@@]27[C@@](CC(OC7)=O)([H])O1)=O)=O. InChi Code: InChI=1S/C26H30O8/c1-22(2)15-9-16(27)24(4)14(25(15)12-31-18(28)10-17(25)33-22)5-7-23(3)19(13-6-8-30-11-13)32-21(29)20-26(23,24)34-20/h6,8,11,14-15,17,19-20H,5,7,9-10,12H2,1-4H3/t14-,15-,17-,19-,20+,23-,24-,25+,26+/m0/s1. InChi Key: KBDSLGBFQAGHBE-MSGMIQHVSA-N.