Lanepitant 2HCl

Description: Lanepitant 2HCl is a non-peptide neurokinin-1 receptor antagonist with analgesic and anti-inflammatory activity.Lanepitant 2HCl inhibits the binding of Substance P to the neurokinin-1 receptor, inhibits neurogenic inflammation and pain transmission, and can be used in the study of painful neuropathic disorders, such as migraines. Target: Neurokinin receptor. Smiles: COC(C=CC=C1)=C1CN(C(C)=O)C[C@H](NC(CN2CCC(N3CCCCC3)CC2)=O)CC4=CNC5=CC=CC=C45.Cl.Cl. References: Goldstein DJ,et al. Lanepitant, an NK-1 antagonist, in migraine prevention. Cephalalgia. 2001 Mar,21(2):102-6.