L-Canaline

L-Canaline is an aminooxy analog of ornithine that irreversibly inhibits aminotransferases (transaminases), including ornithine aminotransferase (Ki = 2 µM). It forms oximes with alpha-keto acids and aldehydes, most notably with pyridoxal phosphate, an essential cofactor of aminotransferases. L-Canaline is naturally found in plants, including legumes, and is involved in the metabolism of L-canavanine, an aminooxy analog of arginine. It is cytotoxic to a range of organisms, including bacteria, insects, and parasites.Formal Name: O-amino-L-homoserine. CAS Number: 496-93-5. Molecular Formula: C4H10N2O3. Formula Weight: 134.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 1 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: N[C@@H](CCON)C(O)=O. InChi Code: InChI=1S/C4H10N2O3/c5-3(4(7)8)1-2-9-6/h3H,1-2,5-6H2,(H,7,8)/t3-/m0/s1. InChi Key: FQPGMQABJNQLLF-VKHMYHEASA-N.