Isoforskolin

Description: Isoforskolin is derived from Coleus forskohlii and reduces the secretion of TNF-alpha, IL-1beta, IL-6 and IL-8 in human mononuclear leukocytes. Isoforskolin can be used in studies about the treatment of Lyme arthritis. Target: IL Receptor, TNF. Smiles: [H][C@@]12[C@H](OC(C)=O)[C@H](O)[C@@]3(C)O[C@](C)(CC(=O)[C@]3(O)[C@@]1(C)[C@@H](O)CCC2(C)C)C=C. References: Zhao H, et al. Isoforskolin downregulates proinflammatory responses induced by Borrelia burgdorferi basic membrane protein A.Exp Ther Med. 2017 Dec,14(6):5974-5980.