IR-783

Dark red to brown powder. Soluble in water or methanol. Chemical. CAS: 115970-66-6. Formula: C38H46ClN2NaO6S2. MW: 749.37. Synthetic. IR-783 is a functional laser and near-IR (NIR) dye. Spectral data: Absorption lambdamax=783nm (MeOH). IR-783 has been shown to be a dye that exhibits imaging, cancer targeting and anticancer properties. Useful optical probe for NIR imaging of tumors, shown to accumulate in the mitochondria and lysosomes of cancer cells. IR-783 inhibits cell viability and induces mitochondrial apoptosis in human breast cancer cells and induces cell proliferation in a dose- and time-dependent manner by inducing cell cycle arrest at the G0/G1 phase.