IDO-IN-1

IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor that demonstrates IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays, respectively. It is inactive against tryptophan 2,3-dioxygenase (TOD, IC50 > 10 µM).Formal Name: 4-amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide. CAS Number: 914638-30-5. Molecular Formula: C9H7BrFN5O2. Formula Weight: 316.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml, Ethanol:PBS (pH 7.2) (1:30): 0.025 mg/ml. lambdamax: 238, 282 nm. SMILES: FC1=CC=C(/N=C(C2=NON=C2N)\NO)C=C1Br. InChi Code: InChI=1S/C9H7BrFN5O2/c10-5-3-4(1-2-6(5)11)13-9(14-17)7-8(12)16-18-15-7/h1-3,17H,(H2,12,16)(H,13,14). InChi Key: ORHZJUSHZUCMKR-UHFFFAOYSA-N.