HQNO

HQNO is an inhibitor of the respiratory chain binding to the mitochondrial cytochrome b protein, a component of complex III. In Vibrio alginolyticus, HQNO blocks 90% the activity of the sodium transporting NADH oxidase at a concentration of 40 µM. It is a useful tool for probing the mechanisms of electron transfer and proton or sodium translocation by the respiratory chain.Formal Name: 2-heptyl-4-quinolinol 1-oxide. CAS Number: 341-88-8. Synonyms: KF8940, N-oxo-2-heptyl-4-Hydroxyquinoline, Pyo II. Molecular Formula: C16H21NO2. Formula Weight: 259.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 0.5 mg/ml, DMSO: 1 mg/ml, Ethanol: 3 mg/ml, Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml. lambdamax: 214, 242, 330 nm. SMILES: [O-][N+]1=C(CCCCCCC)C=C(O)C2=CC=CC=C21. InChi Code: InChI=1S/C16H21NO2/c1-2-3-4-5-6-9-13-12-16(18)14-10-7-8-11-15(14)17(13)19/h7-8,10-12,18H,2-6,9H2,1H3. InChi Key: NZPACTGCRWDXCJ-UHFFFAOYSA-N.