Homo-PROTAC pVHL30 degrader 1

Description: Homo-PROTAC pVHL30 degrader 1 is a potent PROTAC-based degrader of pVHL30. Target: Others, PROTACs. Smiles: C([C@@H](NC(COCCOCCOCC OCCOCCOCC(N[C@H](C(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1)[C@@](C)(C)C)=O)=O)[C@@](C)(C)C)(=O)N4[C@H](C(NCC5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](O)C4. References: Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10,8(1):830.