Hederasaponin B

Hederasaponin B is a triterpene saponin that has been found in H. helix and has antiviral and antioxidant activities. It inhibits the cytopathic effect induced by the enterovirus 71 (EV71) genotypes C3 and C4a (EC50s = 24.77 and 41.77 µg/ml, respectively), as well as reduces expression of the viral structural capsid protein VP2, in Vero cells. Hederasaponin B (100, 150, and 200 µg/ml) inhibits superoxide generation in human neutrophils.Formal Name: 3beta-[[2-O-(6-deoxy-alpha-L-mannopyranosyl)-alpha-L-arabinopyranosyl]oxy]-olean-12-en-28-oic acid, O-6-deoxy-alpha-L-mannopyranosyl-(1->4)-O-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl ester. CAS Number: 36284-77-2. Synonyms: Hederacoside B, Hederagenin B. Molecular Formula: C59H96O25. Formula Weight: 1205.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, PBS (pH 7.2): 5 mg/ml. SMILES: CC1(C)CC[C@]2(C(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]4O[C@H](CO)[C@@H](O[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@H](O)[C@H]4O)O3)=O)CC[C@@]6(C)[C@]([C@]7([H])CC=C6[C@]2([H])C1)(C)CC[C@@]([C@]7(C)CC8)([H])C(C)(C)[C@H]8O[C@@H]9OC[C@H](O)[C@H](O)[C@H]9O[C@H]%10[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O%10. InChi Code: InChI=1S/C59H96O25/c1-24-34(62)38(66)42(70)49(77-24)82-46-29(21-60)79-48(45(73)41(46)69)76-23-30-37(65)40(68)44(72)51(80-30)84-53(74)59-18-16-54(3,4)20-27(59)26-10-11-32-56(7)14-13-33(55(5,6)31(56)12-15-58(32,9)57(26,8)17-19-59)81-52-47(36(64)28(61)22-75-52)83-50-43(71)39(67)35(63)25(2)78-50/h10,24-25,27-52,60-73H,11-23H2,1-9H3/t24-,25-,27-,28-,29+,30+,31-,32+,33-,34-,35-,36-,37+,38+,39+,40-,41+,42+,43+,44+,45+,46+,47+,48+,49-,50-,51-,52-,56-,57+,58+,59-/m0/s1. InChi Key: NVSLBOBPSCMMSO-BVLVEXITSA-N. Origin: Plant/Rhizoma Anemones Raddeanae.