HDAC6-IN-13

Description: HDAC6-IN-13 (Compound 35m) is a potent and highly selective orally active inhibitor of HDAC6, with an IC50 of 0.019 µM. It also inhibits HDAC1, HDAC2, and HDAC3, with IC50 values of 1.53 µM, 2.06 µM, and 1.03 µM, respectively. HDAC6-IN-13 exhibits substantial blood-brain barrier permeability and anti-inflammatory properties [1]. Target: Others