Harzianol J

Description: Harzianol J is a harziane-type diterpene compound isolated from the deep-sea sediment fungus Trichoderma sp. SCSIOW21. It exhibits anti-inflammatory activity, achieving an 81.8% inhibition rate of NO at a concentration of 100 µM, with an IC50 value of 66.7 µM for NO production inhibition. Harzianol J is applicable in anti-inflammatory research. Target: NO Synthase. Smiles: C[C@]1(C)[C@]23[C@]([C@@]4(C)[C@@]([C@H](C)CC2)(C(=O)C4)[H])(C[C@@]1(C(=O)C[C@H]3C)[H])[H]